AbdElRady, H., AbdElReheim, M., AbdelHafiz, I. (2017). UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST. test, 6(2), 213-222. doi: 10.21608/sinjas.2017.78787
Hend S. AbdElRady; Mohamed A.M. AbdElReheim; Ibrahim S. AbdelHafiz. "UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST". test, 6, 2, 2017, 213-222. doi: 10.21608/sinjas.2017.78787
AbdElRady, H., AbdElReheim, M., AbdelHafiz, I. (2017). 'UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST', test, 6(2), pp. 213-222. doi: 10.21608/sinjas.2017.78787
AbdElRady, H., AbdElReheim, M., AbdelHafiz, I. UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST. test, 2017; 6(2): 213-222. doi: 10.21608/sinjas.2017.78787

UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST

Sinai Journal of Applied Sciences
Article 13, Volume 6, Issue 2, August 2017, Pages 213-222    PDF (559.08 K)
DOI: 10.21608/sinjas.2017.78787
Authors
Hend S. AbdElRady* ; Mohamed A.M. AbdElReheim; Ibrahim S. AbdelHafiz
Dept. Chem., Fac. Sci, Arish Univ., Egypt.
Abstract
Many heterocyclic compounds were prepared from the reaction of 2-imino-6-phenyl-2,3-dihydropyrimidin-4(5H)-one 4 with some bifunctional nucleophiles and electrophiles reagents under mild conditions .The structure of the synthesized compounds were established via their elemental and spectral analysis. Some of the products were also screened in vitro for their biological activity.
Keywords
Iminopyrimidine; pyrazolopyrimidin; dihydropyrimidin; dihydropyridine carbonitrile; pyrimidin-6-ylformimidate
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