Comparison of intensity modulated and 3- dimensional conformal radiotherapy for prostate cancer using 6-MV and 15-MV photon energies | ||
| Arab Journal of Nuclear Sciences and Applications | ||
| Article 20, Volume 53, Issue 2, April 2020, Pages 189-200 PDF (447.27 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ajnsa.2020.19402.1296 | ||
| Authors | ||
| Jamal AL-Shareef* 1; Ehab Attalla2; magdy Khalil3; Ahmed M Abdelaal ‎4 | ||
| 1Medical Biophysics, Sana'a University, Sana'a, Yemen | ||
| 2Department of Radiotherapy and Nuclear Medicine, National Cancer Institute, Cairo University, ‎Cairo, Egypt | ||
| 3Physics Department, Faculty of Science, Helwan University, Cairo, Egypt | ||
| 4‎ Radiotherapy Department, Nasser Institute, Cairo, Egyp | ||
| Abstract | ||
| Prostate cancer is one of the commonest cancers in men. The purpose of this work was to compare between intensity-modulated radiotherapy (IMRT) versus three-dimensional conformal radiotherapy (3D-CRT) planning in patients with prostate cancer using 6-MV and 15-MV photon energies. Twenty patients with localized prostate cancer were planned on Xio treatment planning system. Four treatment plans were generated for each patient. IMRT whether 6 or 15 MV beam was slightly better in terms of target coverage but not significant (p>0.05) in comparison to 3D-CRT in both beam energies. IMRT was better than 3D-CRT in terms of organs at risk (OARs) sparing and conformity index (CI) in both 6 and 15-MV whereas 3D-CRT in both 6 and 15-MV yielded better homogeneity index (HI) compared to IMRT 6 and 15-MV. The number of monitor units (MU) increased in IMRT compared to 3D-CRT. Also, MU increased in low energy compared to high energy whether in 3D-CRT or IMRT (p<0.05). When IMRT 6-MV and IMRT 15-MV were compared, no significant difference was found in terms of target coverage and OARs except the rectum was better in IMRT 6-MV compared to IMRT 15-MV. IMRT 6-MV technique should be prioritized when user has options for treatment and then 3D-CRT as a second line when the former is not available. The choice of the energies (6 and 15MV) used with 3D-CRT depend largely on patient's body geometry while the use of high energy IMRT 15-MV is not recommended. | ||
| Keywords | ||
| Intensity modulated radiotherapy; 3D-conformal radiotherapy; high energy; prostate cancer | ||
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