Quality Control Criteria of Volatile Ingredients in Certain Mouthwash Products in the Egyptian Market | ||
| Egyptian Journal of Chemistry | ||
| Article 29, Volume 63, Issue 11, November 2020, Pages 4493-4501 PDF (982.45 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2020.26576.2540 | ||
| Authors | ||
| Elsayed Abotabl1; Mai Khader2; Rehab Elshemy* 2; Mona Morad1 | ||
| 1Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt. | ||
| 2Department of Medicinal Plants and Natural Products, National Organization for Drug Control and Research, Dokki, Cairo, Egypt. | ||
| Abstract | ||
| Quality control criteria of active volatile ingredients in the commercial mouthwash products are not sufficient and not probably specify the quantity of active herbal ingredients. Therefore, it is important to apply the most recent advanced techniques including chromatographic methods as GC, HPLC and HPTLC for analysis of these active volatile ingredients. Comparison of different methods was carried out depending on their validation parameters to choose the best method for analysis.. The total amount of volatile ingredients in all the selected mouthwashes was in the effective limit. HPTLC was the simplest method for identification of volatile ingredients. Moreover, HPLC technique was recommended instead of GC for determination of volatile ingredients that have chromophore in the commercial mouthwash products as resulted from their validation parameters, as well as GC analysis needs a lot of extraction solvent that lead to loss of active volatiles. | ||
| Keywords | ||
| Quality control; mouthwash; volatile ingredients; HPLC; HPTLC; GC | ||
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