Role of Ketamine as an Adjuvant to Bupivacaine in C-Arm Guided Thoracic Paravertebral Block Analgesia for Modified Radical Mastectomy | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 13, Volume 71, Issue 5, April 2018, Pages 3153-3157 PDF (209.36 K) | ||
| Document Type: Original Article | ||
| Author | ||
| Sanaa Mohamed Elnoamany 1, Nabil Ali El Sheikh 1, Asmaa Fawzy Amer 1, Areeg Kotb Ghalwash 2 | ||
| 1 Anethesiology & Surgical I.C.U, Faculty of Medicine, Tanta University, 2 M.B.B.CH | ||
| Abstract | ||
| Background: Breast cancer is the most common type of cancer found in women and today represents a significant challenge to public health. Postoperative pain is the most distressing symptom experienced by the patient. Pain induces metabolic, hormonal and cardio-respiratory responses that affect the outcome of surgery. Aim of the Work: The aim of this study was to evaluate the role of ketamine as an adjuvant to bupivacaine in c- arm guided thoracic paravertebral block analgesia for modified radical mastectomy. Patients and Methods: This study was carried out in Tanta University Hospitals in Surgery Department from April 2016 to October 2016 on sixty-two patients scheduled for elective modified radical mastectomy divided into two equal groups each contain 31 patients, group 1 received PVB with bupivacaine only under c arm and group 2 received PVB with bupivacaine and ketamine as pre emptive analgesia and watch what is the outcome. Written informed consent was taken from each patient. Results: This prospective randomized double blind study was carried out on 62 patients divided into two equal groups where group two showed statistically significant decrease in VAS , total amount of analgesic and delay in time of first analgesic requirement in comparison with group one and significant difference as regard hemodynamics and postoperative complication between two groups. Conclusion: We concluded that addition of ketamine to bupivacaine as an adjuvant in C-arm guided PVB appears to be more beneficial than the use of bupivacaine alone for postoperative analgesia in modified radical mastectomy surgery. | ||
| Keywords | ||
| Ketamine; Bupivacaine; Radical mastectomy; C-Arm Guided Thoracic Paravertebral; Block Analgesia | ||
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