Role of Diffusion Weighted MR Imaging in Assessment of Hepatocellular Carcinoma after Radiofrequency Ablation | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 24, Volume 71, Issue 5, April 2018, Pages 3229-3231 PDF (433.66 K) | ||
| Document Type: Original Article | ||
| Author | ||
| Hossam Fahmy Abdel Hamid, Ahmed Hassan Soliman, Jalal Khaleel Abduljaleel | ||
| Department of Radio-diagnosis, Faculty of Medicine, Ain Shams University | ||
| Abstract | ||
| Background: hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Surgical resection and local ablative therapies represent the most frequent first lines therapies adopted when liver transplantation cannot be offered. Aim of the work: this study aimed to evaluate the feasibility of DWI and the corresponding ADC values to detect tumor response after radiofrequency ablation for hepatocellular carcinoma. Patients and methods: MR examinations were done for 20 HCC patients post-RFA. Pre and post gadolinium enhanced images as well as DW sequences were performed. ADC values of ablation zones and liver parenchyma were assessed. ADC values of ablation zones and adjacent signal alterations identified in DWI were analyzed. Results: residual or recurrent lesions were detected in 4 patients (20%). The mean ADC value of ablated zones differed significantly from that of normal liver parenchyma. The corresponding ADC values were significantly lower in patients with residual lesion than in patients without residual lesion. Conclusion: it can be concluded that DWI is a feasible follow-up tool for post ablation liver contributing in detection of residual lesion. | ||
| Keywords | ||
| MRI; carcinoma; Radiofrequency ablation; liver tumor | ||
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