Lipid Profile in Relation to Severity of Liver Diseases | ||
| Benha Medical Journal | ||
| Article 15, Volume 37, Issue 1, May 2020, Pages 319-325 PDF (950.84 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2020.89513 | ||
| Authors | ||
| Ahmed Goma1; Mahmoud Sharafeddin1; Amany AbdAllah2 | ||
| 1Department of Internal Medicine, Faculty of Medicine, Zagazig University, Egypt | ||
| 2Department of Family Medicine, Faculty of Medicine, Zagazig University | ||
| Abstract | ||
| Background: Liver cirrhosis is a life-threatening condition. It is very prevalent in Egypt. Lipids are stored and metabolized in the liver. Liver cirrhosis has an essential influence on the lipid profile. Objectives: Evaluation of the lipid profile via assessing triglyceride (TG), total cholesterol, very low-density lipoprotein, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) in cirrhotic patients and define its relationship to Child score. Patients and methods: This cross-sectional study was carried out in the Internal Medicine Department outpatient clinic, Zagazig University Hospital, Egypt. Ninety patients with liver cirrhosis were enrolled in the study. Fasting lipid profile was done. Comparison of the lipid profile in different Child classes in cirrhotic was done. Results: Total cholesterol, HDL, LDL, VLDL, and TG were compared in different childturcotte-pugh (CTP) classes. The data was analyzed on SPSS 21. Results showed significantly low levels of total cholesterol, HDL, LDL as the CTP class advances and also lower levels as compared with the control group. However, a statistically non-significant decrease in TG was observed. Conclusion: Total cholesterol, HDL, and LDL levels are significantly reduced in patients who develop liver cirrhosis and levels further decrease as the CTP classadvances. Keywords: CTP score, lipid profile, | ||
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