FORMULATION AND STABILITY OF HEPTAMINOL DROPS | ||
| Bulletin of Pharmaceutical Sciences Assiut University | ||
| Article 1, Volume 7, Issue 2, December 1984, Pages 251-260 PDF (327.1 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfsa.1984.89688 | ||
| Authors | ||
| Ali A. Kassem; Mohamed F. El-Miligi; Siham A. Ali | ||
| Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt | ||
| Abstract | ||
| Several aqueous solvents were tried for the formulation of Heptaminol base in oral drops. Also, some stabilizing agents were evaluated for their action on the stability of Heptaminol base in the selected solvents. It was observed that distilled water conferred the best stability to Heptaminol base even when compared to market drope. Inclusion of 0.1 percent sodium thiosulphate in the latter solvent seems to be ineffective for further stabilization. In other solvents, the antioxidants tried largely detracted from the stability of Heptaminol base. In addition, 50 percent sorbitol in water was clearly found the worst solvent with regards to Heptaminol stability. | ||
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