El-Olemy, M., Kadry, H. (1984). WITHANOLIDES OF WITHANIA SOMNIFERA L. DUNAL GROWING WILD IN EGYPT. test, 7(2), 430-443. doi: 10.21608/bfsa.1984.89873
M. M. El-Olemy; H. A. Kadry. "WITHANOLIDES OF WITHANIA SOMNIFERA L. DUNAL GROWING WILD IN EGYPT". test, 7, 2, 1984, 430-443. doi: 10.21608/bfsa.1984.89873
El-Olemy, M., Kadry, H. (1984). 'WITHANOLIDES OF WITHANIA SOMNIFERA L. DUNAL GROWING WILD IN EGYPT', test, 7(2), pp. 430-443. doi: 10.21608/bfsa.1984.89873
El-Olemy, M., Kadry, H. WITHANOLIDES OF WITHANIA SOMNIFERA L. DUNAL GROWING WILD IN EGYPT. test, 1984; 7(2): 430-443. doi: 10.21608/bfsa.1984.89873

WITHANOLIDES OF WITHANIA SOMNIFERA L. DUNAL GROWING WILD IN EGYPT

Bulletin of Pharmaceutical Sciences Assiut University
Article 16, Volume 7, Issue 2, December 1984, Pages 430-443    PDF (474.54 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1984.89873
Authors
M. M. El-Olemy1; H. A. Kadry2
1Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt
2Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
Abstract
 Three Withanolides (Substances A,B, and C) were isolated from the alcoholic extract of the Egyptian Withania somnifera wild plants. Substance A and substance C were identified by IR, NMR and Mass spectral data. Substance A appears to be a configurational isomer of Withanolide E and substance C is 4-hydroxy derivative of substance A. Substance A is identified as 14,17,20-trihydroxy-5B,6B-epoxy-1-oxo-Witha-2,24-dienolide (I) and substance C as 4,14,17,20-tetrahydroxy-5B, 6B-epoxy-1-oxo-witha-2,24-dienolide(II).
This is the first report of isolation and characterization of substance C from Withania somnifera or the genus Withania. Substance B would be the subject of a further report.
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