Hassan, A., Attia, H., A.E. El Din, D. (2018). Immediate and Short-term Changes in Left Ventricular Function in Children Undergoing Percutaneous Closure of Patent Ductus Arteriosus by Echocardiography and Tissue Doppler. test, 72(3), 4085-4092. doi: 10.21608/ejhm.2018.9121
Ahmed M. Hassan; Hebatallah M. Attia; Dina A.E. El Din. "Immediate and Short-term Changes in Left Ventricular Function in Children Undergoing Percutaneous Closure of Patent Ductus Arteriosus by Echocardiography and Tissue Doppler". test, 72, 3, 2018, 4085-4092. doi: 10.21608/ejhm.2018.9121
Hassan, A., Attia, H., A.E. El Din, D. (2018). 'Immediate and Short-term Changes in Left Ventricular Function in Children Undergoing Percutaneous Closure of Patent Ductus Arteriosus by Echocardiography and Tissue Doppler', test, 72(3), pp. 4085-4092. doi: 10.21608/ejhm.2018.9121
Hassan, A., Attia, H., A.E. El Din, D. Immediate and Short-term Changes in Left Ventricular Function in Children Undergoing Percutaneous Closure of Patent Ductus Arteriosus by Echocardiography and Tissue Doppler. test, 2018; 72(3): 4085-4092. doi: 10.21608/ejhm.2018.9121

Immediate and Short-term Changes in Left Ventricular Function in Children Undergoing Percutaneous Closure of Patent Ductus Arteriosus by Echocardiography and Tissue Doppler

The Egyptian Journal of Hospital Medicine
Article 9, Volume 72, Issue 3, July 2018, Pages 4085-4092    PDF (330.21 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2018.9121
Authors
Ahmed M. Hassan; Hebatallah M. Attia; Dina A.E. El Din
Department of Cardiology, Faculty of Medicine, Ain Shams University
Abstract
Background: Patent ductus arteriosus accounts for 5–10% of all congenital heart diseases. Left-to-right shunting through the PDA results in pulmonary over-circulation and left heart volume overload. Transcatheter closure is the method of choice for PDA closure when suitable. Some previous studies have described an immediate deterioration of left ventricular functions after percutaneous closure of PDA, which is reversible and improves after few months. Purpose: This study aimed to determine the immediate and short-term changes in the left ventricular function in children with patent ductus arteriosus after percutaneous closure using 2D echocardiography and tissue doppler imaging. Patients and Methods: Thirty children with isolated PDA were treated by trans-catheter closure were studied. The LV dimensions, volumes and systolic function were assessed by two-dimensional echocardiography and tissue Doppler imaging before the PDA closure, on day 1 and after one month. Results: The median age of the patients was 4.25 years and mean BSA was 0.73 ± 0.31 m2, with the mean PDA diameter of 2.53 ± 0.60 mm. The LVEDD, LVESD, left atrium diameter, ejection fraction and LVEDV reduced significantly immediately after PDA closure (p < 0.001). After 1 month, LVEDD, LVESD and LAD continued to decrease, while ejection fraction improved significantly. All tissue Doppler velocities showed a significant decrease immediately after closure with significant increase of MPI (p < 0.001) and then were improved within 1 month. Conclusion: percutaneous closure of PDA was associated with reversible significant decrease in the left ventricular systolic and diastolic functions, which recovered after one month.
Keywords
Left Ventricular Function; Echocardiography and tissue Doppler; patent ductus arteriosus
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