Qorban, G., Badghaish, M., Albaqami, A., Nemer, A., Alali, A., Al Yaqoub, R., Alshamrani, H., Badahman, O., Ansaif, R., Alasmari, M., Alghamdi, A., Alshareef, H., Aljadeed, A., Almohammed, A., Filmban, D., Alaql, A. (2018). Rheumatoid Arthritis, Pathophysiology and Management. test, 70(11), 1898-1903.
Ghofran Noor Mohammad Qorban; Mohannad Mobarak Omar Badghaish; Abdulmohsen Shawan Albaqami; Ameera Ahmad Nemer; Aisha Jamal Alali; Rawan Fouad Hassan Al Yaqoub; Homoud Abdulaziz Alshamrani; Omar Hasan Badahman; Rahma Abdulkarim Ansaif; Metab Ali Alasmari; Arwa Yahya Alghamdi; Hussain Ahmad Saud Alshareef; Alanoud Mohammed Aljadeed; Ayman Ahmed Almohammed; Doaa Mohammad Filmban; Abdulrahman Saleh Alaql. "Rheumatoid Arthritis, Pathophysiology and Management". test, 70, 11, 2018, 1898-1903.
Qorban, G., Badghaish, M., Albaqami, A., Nemer, A., Alali, A., Al Yaqoub, R., Alshamrani, H., Badahman, O., Ansaif, R., Alasmari, M., Alghamdi, A., Alshareef, H., Aljadeed, A., Almohammed, A., Filmban, D., Alaql, A. (2018). 'Rheumatoid Arthritis, Pathophysiology and Management', test, 70(11), pp. 1898-1903.
Qorban, G., Badghaish, M., Albaqami, A., Nemer, A., Alali, A., Al Yaqoub, R., Alshamrani, H., Badahman, O., Ansaif, R., Alasmari, M., Alghamdi, A., Alshareef, H., Aljadeed, A., Almohammed, A., Filmban, D., Alaql, A. Rheumatoid Arthritis, Pathophysiology and Management. test, 2018; 70(11): 1898-1903.

Rheumatoid Arthritis, Pathophysiology and Management

The Egyptian Journal of Hospital Medicine
Article 5, Volume 70, Issue 11, January 2018, Pages 1898-1903    PDF (242.34 K)
Document Type: Original Article
Authors
Ghofran Noor Mohammad Qorban1; Mohannad Mobarak Omar Badghaish* 2; Abdulmohsen Shawan Albaqami3; Ameera Ahmad Nemer4; Aisha Jamal Alali5; Rawan Fouad Hassan Al Yaqoub6; Homoud Abdulaziz Alshamrani7; Omar Hasan Badahman2; Rahma Abdulkarim Ansaif8; Metab Ali Alasmari9; Arwa Yahya Alghamdi4; Hussain Ahmad Saud Alshareef10; Alanoud Mohammed Aljadeed6; Ayman Ahmed Almohammed11; Doaa Mohammad Filmban12; Abdulrahman Saleh Alaql13
1King Abdulaziz University Hospital
2King Abdulaziz University
3Imam Muhammad Ibn Saud Islamic University
4Immam Abdulrahman Faisal University
5Arabian Gulf University
6Ibn Sina National College
7Primary Health Care Center – Riyadh
8Alexandria University
9Gizan Militarily Hospital
10King Fahad Hospital, Madinah
11King Faisal University
12Al Noor Specialist Hospital
13Al Adeel Primary Health Care Center
Abstract
Introduction: Rheumatoid arthritis is considered one of the most common, and particularly attacks the joint causing significant individual and community burden, and present with articular as well as extra articular manifestation. Treatment modalities of rheumatoid arthritis have dramatically improved in recent years, significantly decreasing long-term auricular and extra-auricular complications.
Aim of the work: this review was aimedto study the pathophysiology, clinical picture, and management of rheumatoid arthritis, with focus on the newer modalities.  
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: rheumatoid arthritis, chronic inflammatory disorders, genetic of rheumatoid arthritis, management of rheumatoid arthritis, DMARD, biological agents
Conclusion: The newer modality of treatment must include disease-modifying antirheumatic drug (DMARDs) which must be started as early as possible. Combining DMARDs with corticosteroids will result in significantly better outcomes than monotherapy with any DMARD and decrease long term morbidity associated with this condition.
Keywords
chronic inflammatory disorders; management of rheumatoid arthritis; DMARD; Biological agents; Rheumatoid Arthritis
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