Hamed, A., Beshr, A., Behairy, R., Eladawy, I. (2020). Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS). test, 2(3), 547-553. doi: 10.21608/ijma.2020.27101.1119
Alaa Ameen Hamed; Amal Elsebaie Beshr; Reda Mohamed Behairy; Iman Ibrahim Eladawy. "Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)". test, 2, 3, 2020, 547-553. doi: 10.21608/ijma.2020.27101.1119
Hamed, A., Beshr, A., Behairy, R., Eladawy, I. (2020). 'Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)', test, 2(3), pp. 547-553. doi: 10.21608/ijma.2020.27101.1119
Hamed, A., Beshr, A., Behairy, R., Eladawy, I. Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS). test, 2020; 2(3): 547-553. doi: 10.21608/ijma.2020.27101.1119

Vestibular Evoked Myogenic Potential in Multiple Sclerosis (MS)

International Journal of Medical Arts
Article 9, Volume 2, Issue 3, July 2020, Pages 547-553    PDF (377.2 K)
Document Type: Original Article
DOI: 10.21608/ijma.2020.27101.1119
Authors
Alaa Ameen Hamed1; Amal Elsebaie Beshr2; Reda Mohamed Behairy2; Iman Ibrahim Eladawy* 2
1Resident at Department of Otorhinolaryngology [Audiovestibular Unit], Faculty of Medicine for Girls, Al-Azhar University, Egypt
2Department of Otorhinolaryngology, Faculty of Medicine for Girls [Cairo], Al-Azhar University, Egypt
Abstract
Background: Involvement of the brainstem in multiple sclerosis [MS] has significant implications on the disease course and can be presented with different symptoms. There are many tests able to detect brain-stem involvement in MS with various degrees of success.
Aim of the work: To study the changes in vestibular evoked myogenic potential [VEMP], in patients with MS, and to detect its sensitivity for detection of the brain-stem lesions previously diagnosed with magnetic resonance imaging [MRI] in MS patients.
Patients and Methods: Sixty participants had been enrolled and divided into two groups: 30 healthy subjects [Control group] and 30 MS patients [Study group]. Both groups had been subjected to otological examinations, pure tone audiometry, acoustic impedance, cervical vestibular evoked myogenic potential [cVEMP], ocular vestibular evoked myogenic potential [oVEMP] and MRI. 
Results: In MS group, oVEMP mean latencies of n1 and p1 and cVEMP mean p13 and n23 latencies were significantly prolonged. In addition, 14 MS patients [46.7%] had brainstem lesions as confirmed by MRI. Finally, oVEMP test had higher sensitivity than the cVEMP in prediction of brainstem lesions.
Conclusion: oVEMP seems to be useful and more sensitive than cVEMP as an adjunct test in the evaluation of brain-stem dysfunction in MS patients. 
Keywords
Multiple Sclerosis [MS]; Vestibular Evoked Myogenic Potential [VEMP]; Cervical; Vestibular function; Ocular
Statistics
Article View: 555
PDF Download: 453