Relation between anti-thyroid peroxidase antibody and recurrent pregnancy loss: A case control study | ||
| Evidence Based Women's Health Journal | ||
| Article 8, Volume 10, Issue 2, May 2020, Pages 176-180 PDF (957.69 K) | ||
| Document Type: Case Report | ||
| DOI: 10.21608/ebwhj.2020.28672.1095 | ||
| Authors | ||
| Mohamed Sayed Ali1; Rehab Mohamed Abdel Rahman2; Nancy Samir Wahba3; Mohamed Gaber* 4 | ||
| 1Department of Obstetrics and Gynecology, Ain-Shams University, Cairo | ||
| 2Department of Obstetrics and Gynecology, Faculty of Medicine, Ain-Shams University. | ||
| 3Department of Clinical Pathology, Faculty of Medicine, Ain-Shams University, Cairo | ||
| 4Obstetrics and Gynecology Department, Faculty of Medicine, Kafr Elsheikh University | ||
| Abstract | ||
| Background: Thyroid dysfunction and autoimmunity are relatively common clinical scenario in women within reproductive age group and have been correlated and linked to a spectrum of adverse pregnancy outcomes such as recurrent miscarriage. Aim: To investigate the correlation and linkage between anti-TPO antibody and recurrent miscarriage. Materials and Methods: This case control observational research study was conducted on 90 pregnant female out which 45 with history of recurrent miscarriage were cases and 45 without such history were controls. Results: The mean age of control group was 25.29 while it was 26.69 in cases group. The prevalence of anti-tpo antibody positivity in the study group was 18.8%.out of 90 pregnant female ;17 were positive for anti-tpo antibody. The prevalence of thyroid autoimmunity in pregnant women with recurrent abortion was (37.8%) while it was (0%) in the healthy group (P=0.0). Conclusion:There was significant relationship between anti thyroid antibody positivity and recurrent miscarriage. Thyroid autoimmunity can be considered as risk marker for recurrent miscarriage. | ||
| Keywords | ||
| Anti-tpo antibody; pregnancy; recurrent miscarriage | ||
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