Ahmed, M., Kobiesy, M., Hafez, M., Bakr, A. (2020). Thyroid Dysfunction and Critical Illness in Intensive Care Unit Patients of Aswan University Hospital. test, 80(2), 835-844. doi: 10.21608/ejhm.2020.100198
Marwa Ahmed Abdelhameid Ahmed; Mohammad Alyamany Kobiesy; Mohamed Zein EL-Dein Hafez; Asmaa Osama Bakr. "Thyroid Dysfunction and Critical Illness in Intensive Care Unit Patients of Aswan University Hospital". test, 80, 2, 2020, 835-844. doi: 10.21608/ejhm.2020.100198
Ahmed, M., Kobiesy, M., Hafez, M., Bakr, A. (2020). 'Thyroid Dysfunction and Critical Illness in Intensive Care Unit Patients of Aswan University Hospital', test, 80(2), pp. 835-844. doi: 10.21608/ejhm.2020.100198
Ahmed, M., Kobiesy, M., Hafez, M., Bakr, A. Thyroid Dysfunction and Critical Illness in Intensive Care Unit Patients of Aswan University Hospital. test, 2020; 80(2): 835-844. doi: 10.21608/ejhm.2020.100198

Thyroid Dysfunction and Critical Illness in Intensive Care Unit Patients of Aswan University Hospital

The Egyptian Journal of Hospital Medicine
Article 13, Volume 80, Issue 2, July 2020, Pages 835-844    PDF (755.94 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2020.100198
Authors
Marwa Ahmed Abdelhameid Ahmed; Mohammad Alyamany Kobiesy; Mohamed Zein EL-Dein Hafez; Asmaa Osama Bakr
Abstract
Background: Thyroid hormones play an essential role in human metabolism. Critical illness is often associated with alterations in thyroid hormone concentrations in patients with no previous intrinsic thyroid disease. Objective: This study was conducted to evaluate frequency of thyroid dysfunction in Intensive Care Unit patients of Aswan University Hospital and to correlate between thyroid dysfunction and susceptibility for mechanical ventilation. Patients and methods: This was a cross-sectional non randomized study was conducted at Internal Medicine Intensive Care Units and Surgical Intensive Care Unit of Aswan University Hospital on 200 patients who were eligible to inclusion/exclusion criteria of the study. Thyroid function test of TSH, FT3 and FT4 levels were investigated for all patients and were compared and correlated with the clinical data of those patients. Results: Thyroid function abnormalities are common in critically ill patients who didn’t have abnormal thyroid functions before and more common in female patients than males. There was a correlation between abnormal thyroid functions in critically ill patients and their mortality and more in sick euthyroid syndrome patients. There was no relation between abnormal thyroid functions in critically ill patients and their increased susceptibility for mechanical ventilation.
Conclusions: Thyroid function abnormalities are common in ICU patients, reflecting the prognosis and affect the clinical outcome for those patients.
Keywords
Thyroid; Critical; Illness; ICU
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