EFFECT OF DIETARY INTERVENTION ON REDUCING LEVEL OF THE HYPERURICEMIA IN EXPERIMENTAL ANIMALS | ||
| Zagazig Journal of Agricultural Research | ||
| Article 14, Volume 43, Issue 1, January 2016, Pages 195-208 PDF (1.15 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zjar.2016.101579 | ||
| Authors | ||
| Hamdy A. Mahdy; Amal H. Emara* | ||
| Nut. Biochem. and Metabolism Dept., Nat. Nut. Inst., Egypt | ||
| Abstract | ||
| This study was carried out to investigate the effect of dietary intervention of different concentrations (5% and 10%) from parsley (seeds and leaves), cherry and tomato on hyperuricemia in rats. This study was carried on 80 male albino rats; Sprague-Dawley strain weighing (130±10 g). The experimental period was 6 weeks. The results showed significant decrease (P<0.05) in serum uric acid and urea nitrogen as compared to positive control (+ve) and also significant decrease (P<0.05) in serum total cholesterol, triglycerides and VLDL-C as compared to control positive group. The best results of histological examination of liver were in rats group treated with 5 and 10% cherry followed by parsley seeds and leaves 10%. While the best histological examinations of kidney were observed in parsley seeds and leaves 10% followed by 5%. It could be concluded that parsley (leaves and seeds), tomato and cherry reduce serum uric acid and urea nitrogen levels and improve kidney and liver functions. | ||
| Keywords | ||
| Dietary; arthritis; uric acid; gout | ||
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