Aboutaleb, A., Abdelzaher, A. (1980). EFFECT OF DIFFERENT ADDITIVES ON THE MICELLAR SOLUBILIZATION OF CHLORAMPHENICOL. test, 3(1), 87-104. doi: 10.21608/bfsa.1980.104720
A. E. Aboutaleb; A. Abdelzaher. "EFFECT OF DIFFERENT ADDITIVES ON THE MICELLAR SOLUBILIZATION OF CHLORAMPHENICOL". test, 3, 1, 1980, 87-104. doi: 10.21608/bfsa.1980.104720
Aboutaleb, A., Abdelzaher, A. (1980). 'EFFECT OF DIFFERENT ADDITIVES ON THE MICELLAR SOLUBILIZATION OF CHLORAMPHENICOL', test, 3(1), pp. 87-104. doi: 10.21608/bfsa.1980.104720
Aboutaleb, A., Abdelzaher, A. EFFECT OF DIFFERENT ADDITIVES ON THE MICELLAR SOLUBILIZATION OF CHLORAMPHENICOL. test, 1980; 3(1): 87-104. doi: 10.21608/bfsa.1980.104720

EFFECT OF DIFFERENT ADDITIVES ON THE MICELLAR SOLUBILIZATION OF CHLORAMPHENICOL

Bulletin of Pharmaceutical Sciences Assiut University
Article 8, Volume 3, Issue 1, 1980, Pages 87-104    PDF (588.96 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1980.104720
Authors
A. E. Aboutaleb; A. Abdelzaher
Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Abstract
The effect of different inorganic and organic additives on the solubility of chloramphenicol by non-ionic surfactant solutions was investigated at two different temperatures. The following additives were used namely polyethylene glycol 600, propylene glycol, glycerol, urea and potassium chloride. Urea produced a slight effect on the solubilizing efficiency of the non-ionic surfactant solutions; on the other hand a more pronounced effect on the solubilizing efficiency of these nonionic micelles was obtained by increasing the concentration of potassium chloride in solutions. For organic additives it was found that the addition of polyethylene glycol 600 increased the solubilizing efficiency of all the non-ionic surfactant solutions than both glycerol and propylene glycol.
Statistics
Article View: 111
PDF Download: 156