Mobarak, L., Yossif, A., Khater, H., Zarad, C., zakaria, Z., Shokry, A., El agawy, W. (2020). The role of microwave ablation in treatment of small and medium sized hepatocellular carcinoma. test, 3(3), 46-59. doi: 10.21608/muj.2020.40394.1018
Lamiaa Mobarak; Ahmed Farid Yossif; Hamada Khater; Carmen Ali Zarad; zeinab zakaria; Ahmed Adel Shokry; Waleed El agawy. "The role of microwave ablation in treatment of small and medium sized hepatocellular carcinoma". test, 3, 3, 2020, 46-59. doi: 10.21608/muj.2020.40394.1018
Mobarak, L., Yossif, A., Khater, H., Zarad, C., zakaria, Z., Shokry, A., El agawy, W. (2020). 'The role of microwave ablation in treatment of small and medium sized hepatocellular carcinoma', test, 3(3), pp. 46-59. doi: 10.21608/muj.2020.40394.1018
Mobarak, L., Yossif, A., Khater, H., Zarad, C., zakaria, Z., Shokry, A., El agawy, W. The role of microwave ablation in treatment of small and medium sized hepatocellular carcinoma. test, 2020; 3(3): 46-59. doi: 10.21608/muj.2020.40394.1018

The role of microwave ablation in treatment of small and medium sized hepatocellular carcinoma

Medicine Updates
Article 12, Volume 3, Issue 3, October 2020, Pages 46-59    PDF (953.21 K)
Document Type: Original Article
DOI: 10.21608/muj.2020.40394.1018
Authors
Lamiaa Mobarak1; Ahmed Farid Yossif2; Hamada Khater3; Carmen Ali Zarad* 4; zeinab zakaria5; Ahmed Adel Shokry6; Waleed El agawy7
1National hepatology and Tropical Medicine Research institute
2Diagnostic radiology department, faculty of medicine, Banha University
3diagnostic radiology department, faculty of medicine, Banha University
4diagnostic radiology faculty of medicine portsaid university
5Hepatogastroenterology and endemic medicine Dept, Kasr Al Ainy hospital, Faculty of Medicine, Cairo University, Egypt
6Ministry of health
7gastroenterology, Hepatology and Infectious diseases, faculty of medicine Port Said University
Abstract
Back ground and aim of work: Microwave ablation (MWA) is effective and safe technique used in treatment of hepatocellular carcinoma (HCC). The aim of this study is to investigate the role of microwave ablation in treatment of small and medium sized hepatocellular Carcinoma.
Methods: This prospective study included 50 patients who underwent microwave ablation for small and medium size hepatocellular carcinoma with abdominal ultrasound guidance. All patients' demographic, laboratory investigations and complications were recorded. To evaluate efficacy of microwave ablation, Contrast-enhanced computed tomography was done one month and repeated three months after the ablation.
Results: Complete ablation of the tumor was done in 92% of small HCC patients (less than or equal 3 cm) whereas in 64% among medium size HCC patients (more than 3 and up to 4 cm). Tumor recurrence was recorded in one patient (4%) with medium size HCC. There was significant decline in serum alpha fetoprotein levels one month after ablation compared to before the procedure. No major complications of the procedure or mortality were reported.
Conclusion: Microwave ablation is safe and effective in small to medium size HCC tumors treatment with no recorded major complications or mortality in addition to acceptable local tumor control.
Keywords
Hepatocellular carcinoma; Microwave ablation; small and medium sized lesions
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