Abouamer, A., Soliman, D., Shaban, H., Anter, N. (2020). Calcium, Magnesium and phosphate deficiency and their Effect on Clinical outcome in Critically Ill child. test, 5(Issue 2 part (2)), 317-322. doi: 10.21608/bjas.2020.135723
A.A. Abouamer; D.R. Soliman; H.M. Shaban; N.M. Anter. "Calcium, Magnesium and phosphate deficiency and their Effect on Clinical outcome in Critically Ill child". test, 5, Issue 2 part (2), 2020, 317-322. doi: 10.21608/bjas.2020.135723
Abouamer, A., Soliman, D., Shaban, H., Anter, N. (2020). 'Calcium, Magnesium and phosphate deficiency and their Effect on Clinical outcome in Critically Ill child', test, 5(Issue 2 part (2)), pp. 317-322. doi: 10.21608/bjas.2020.135723
Abouamer, A., Soliman, D., Shaban, H., Anter, N. Calcium, Magnesium and phosphate deficiency and their Effect on Clinical outcome in Critically Ill child. test, 2020; 5(Issue 2 part (2)): 317-322. doi: 10.21608/bjas.2020.135723

Calcium, Magnesium and phosphate deficiency and their Effect on Clinical outcome in Critically Ill child

Benha Journal of Applied Sciences
Article 25, Volume 5, Issue 2 part (2), February 2020, Pages 317-322    PDF (867.66 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2020.135723
Authors
A.A. Abouamer1; D.R. Soliman1; H.M. Shaban2; N.M. Anter2
1Pediatrics Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
2Clinical and Chemical Pahthology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
Critical illness may trigger an acute phase response which is associated with several metabolic derangements. These include hypocalcaemia, hypophosphatemia and hypomagnesaemia. To determine the incidence and associated risk factors of hypocalcaemia, hypomagnesaemia and hypophosphatemia that develop in critically ill children and their effect on their clinical outcome. 50 child enrolled in our study aged from 1month to 6 years admitted in pediatric intensive care unit in Benha University Hospital. Levels of serum calcium, magnesium and phosphate were measured during admission. The following variables were analyzed: age, gender, diagnosis on admission, clinical severity score on admission OFI (Organ Failure Index) and daily scores PELOD (Pediatric Logistic Organ Dysfunction), length of hospital stay and outcome were analyzed. Out of 50 patients, the frequency of Calcium deficiency was (64%), magnesium deficiency (46%), and phosphate deficiency (57%) on admission. There was negative correlation between calcium level and PELOD (P=0.048), OFI (P=0.001) and period of hospitalization (P=0.002). Patients with hypomagnesaemia on admission had higher PELOD score (P=0.008), higher OFI (P=0.008),prolonged period of hospitalization(P=0.038) and was associated with hypokalemia (P<0.05).
Hypophosphatemia was associated with higher PELOD score (P=0.019) and increased period of hospitalization (P=0.012). Mortality rate increased in patients with hypocalcaemia (P=0.022) and also in patients with hypomagnesaemia (P=0.006). Deficiency of calcium, magnesium and phosphate were common among critically ill children and affected clinical outcome of patient.
Keywords
Hypocalcemia; Hypomagnesemia; Hypophosphatemia; Critical illness; Clinical outcome
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