Synthesis and Characterization of Chelating Phenolic Polymers Containing Metoclopramide Hydrochloride Drug | ||
| Egyptian Journal of Chemistry | ||
| Article 27, Volume 64, Issue 9, September 2021, Pages 4973-4984 PDF (1012.38 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2021.44696.2908 | ||
| Authors | ||
| Sameaa Khammas* ; Selvana Yosef; Tamador Mahmood; Wasan Mahmood; Shahad Taher; Muna Hadi | ||
| Department of Chemistry; College of Science for Women; University of Baghdad; Baghdad-Iraq | ||
| Abstract | ||
| This study in volved synthesis of the chelating phenolic polymers functionalized by Mannich base functional groups. The work included two parts ; part one syntheses of Mannich bases monomers formed by the condensation reaction of P-hydroxy benzaldehyde with different secondary amines and Primary amine (Metoclopramide hydrochloride) have been synthesized. Then part two included synthesis of phenolic chelating polymers containing Mannich bases by condensation Mannich bases which prepared in part one with P-hydroxy benzaldehyde and phenol. These chelating polymers were characterized through (FT-IR) and( 1H-NMR) spectroscopy so measured the thermal stability and study the biological activity of some of the synthesized compounds . | ||
| Keywords | ||
| Metoclopramide; chelating phenolic polymers; Mannich bases | ||
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