Areida, S., Ismail, M., Abdel Hady, E., Osman, A. (2006). Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species. test, 23(1), 287-308. doi: 10.21608/ejhm.2006.17941
S. K. Areida; M. F. Ismail; E. K. Abdel Hady; A. O. Osman. "Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species". test, 23, 1, 2006, 287-308. doi: 10.21608/ejhm.2006.17941
Areida, S., Ismail, M., Abdel Hady, E., Osman, A. (2006). 'Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species', test, 23(1), pp. 287-308. doi: 10.21608/ejhm.2006.17941
Areida, S., Ismail, M., Abdel Hady, E., Osman, A. Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species. test, 2006; 23(1): 287-308. doi: 10.21608/ejhm.2006.17941

Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species

The Egyptian Journal of Hospital Medicine
Article 11, Volume 23, Issue 1, April 2006, Pages 287-308    PDF (1.54 M)
Document Type: Original Article
DOI: 10.21608/ejhm.2006.17941
Authors
S. K. Areida; M. F. Ismail; E. K. Abdel Hady; A. O. Osman
Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Abstract
Hairisanoftheepidermisinmammalsandconsistsoftwolargegroupsofhumanhair proteins.Oneishardα-keratinsandtheotherismatrixproteins.Thepresentinvestigationaimed tocomparetheultrastructuralofthehairscaleusingthescanningelectronmicroscope,andthe proteinsandaminoacidscontentofthekeratininsevenmammalianspecies.
Thevaluesofthehairthickness,x/yferetandhairpatternofthespeciesinthepresent studyconfirmthepresenceofspecies-specificcharacteristicsandultrastructuralvariation.The situationinmandiffersfromthewildmammalsduetodamageofhaircuticlecausedby mechanicalabuse,exposuretoultravioletradiationandchemicaloverprocessing.The maximumamountofextractedproteinsfromhairkeratinwasanalyzedbySDS-PAGE.The electrophoreticpatternsshowedanoveralldegreeofsimilarity.However,differencesexist betweenspeciesintheintensityofstain.Quantitatively,theelectrophoreticpatternsscannedand analyzedusinggelproteinanalyzer.Theresultsshowednodifferencebetweenthemolecular massofsomespecies,butdifferentinmolecularmassdistribution.
Aminoacidcompositionofkeratinofmammalianhairspeciesofthepresentstudy showedsomevariation,especiallyformethionine,isoleucine,lysineandarginine.Theother aminoacidsstudiedaresignificantlypresentinmosthair.Oneofthelateraminoacidis




cysteine.Cysteineisaveryimportantdueto hepresenceofdisulfatecross-links.
 
 
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