Swelem, M., Elkassar, Y., Fawzy, A., Abd Elatty, A., Deghady, A. (2013). Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia. test, 43(1), 75-82. doi: 10.21608/jhiph.2013.19990
Manal Swelem; Yasser Elkassar; Abd Elmoneim Fawzy; Ahmed Abd Elatty; Akram Deghady. "Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia". test, 43, 1, 2013, 75-82. doi: 10.21608/jhiph.2013.19990
Swelem, M., Elkassar, Y., Fawzy, A., Abd Elatty, A., Deghady, A. (2013). 'Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia', test, 43(1), pp. 75-82. doi: 10.21608/jhiph.2013.19990
Swelem, M., Elkassar, Y., Fawzy, A., Abd Elatty, A., Deghady, A. Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia. test, 2013; 43(1): 75-82. doi: 10.21608/jhiph.2013.19990

Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia

Journal of High Institute of Public Health
Article 7, Volume 43, Issue 1, April 2013, Pages 75-82    PDF (56.55 K)
Document Type: Original Article
DOI: 10.21608/jhiph.2013.19990
Authors
Manal Swelem* 1; Yasser Elkassar1; Abd Elmoneim Fawzy1; Ahmed Abd Elatty1; Akram Deghady2
1Department of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, Egypt
2Department of clinical and chemical pathology Alexandria University, Alexandria, Egypt
Abstract
Background: Leptin seems to be a critical factor for overall fetal development. Macrosomia may place the mother and fetus or neonate at risk for adverse outcomes. Objective: to test if leptin level is implicated in macrosomia. Methods: The sample comprised25 cases delivered full term normal weight infants, and 25 cases delivered full term macrosomicinfants. Maternal serum samples and fetal cord samples were withdrawn immediately after birth of the full term infants. Results: Fetal leptin level was higher in macrosomic infants than normal weight infants. No difference in maternal leptin level between both groups was observed. Conclusion: Leptin levels related directly to quantity of body fat tissue in fetal macrosomia as there is leptinresistence causing elevated leptin evels.
Keywords
leptin; Macrosomia
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