The Outcome of Gastroesophageal Reflux Disease after Eradication Therapy of Helicobacter Pylori | ||
| The Medical Journal of Cairo University | ||
| Article 23, Volume 89, December, December 2021, Pages 2421-2429 PDF (349.6 K) | ||
| DOI: 10.21608/mjcu.2021.216076 | ||
| Author | ||
| SAAD ELDEEN M. EL SHEREF, M.D.; HESHAM S. ABD AL SAMIE, M.D. | ||
| The Departments of Internal Medicine* and Clinical Pathology**, Faculty of Medicine, Al-Azhar University, New Dmaitta | ||
| Abstract | ||
| Abstract Background: Helicobacter pylori is a nice of social path-ogen that has sick about half of the world's populace. It continues to be a major health problem worldwide, causing considerable morbidity and mortality due to peptic ulcer disease and gastric cancer. Aim of Study: The goal of our research was to investigate the relationship between H.pylori eradication and development of GERD. Subjects and Methods: A prospective research recruited 189 individuals who triedhelpful for H. pylori and followed them for a year. To identify H. pylori, at least one rapid test, C-urea breath test, and histology were performed, with at least one of them being positive. To establish eradication from H. pylori, all tests were performed. The gastric mucosa is evaluated endoscopically to identify stomach mucosal waste. The severity of GERD symptoms was divided into three sorts: Minor, modest, and sever. Six and twelve months following endoscopic assessment, symptoms were assessed. Results: the nastyphase of the participants was 49.5±0.9 and 55% of them were males. Among the participants there were 28% current smokers and 66.7% were non-alcoholic. Atrophic gastritis appeared among the participants with the percentage 60.3% for open atrophic gastritis. At 12 months and among who could successfully eradicated from H. pylori infection there were 24% developed esophagitis or symptoms. Factors statistically significant associated with GERD were age, smoking and alcohol consumption. Conclusion: H. pylori purgefixes not cause gastro-esophageal reflux illness, according to current evidence. The endoscopic results show that effective eradication does not result in anrise in the rate of esophagitis. | ||
| Keywords | ||
| H. pylori purge; Gastroesophageal reflux disease; Reflux esophagitis | ||
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