Comparative Acute Exposure Study of Abamectin Different Formulations Inducing Physiological and Oxidative Stress Biomarkers in Nile Tilapia, (Oreochromis niloticus). | ||
| Egyptian Academic Journal of Biological Sciences, B. Zoology | ||
| Article 26, Volume 13, Issue 2, December 2021, Pages 223-238 PDF (926.43 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/eajbsz.2021.220560 | ||
| Authors | ||
| Farag A. Gh. Ahmed1; Rasha M. Reda2 | ||
| 1Plant Protection Dept., Faculty of Agriculture, Zagazig University, P.O. Box, 44511, Zagazig, Egypt. | ||
| 2Department of Fish Diseases and Management, Faculty of Veterinary Medicine, Zagazig University, P.O. Box 44511, Zagazig, Egypt. | ||
| Abstract | ||
| The goal of this study is to assess the acute and sublethal potential hazards on tilapia fish (Oreochromis niloticus) exposed to two different commercial formulations of abamectin (ABM, 5%): emulsifiable concentration (EC) and microemulsions (ME). The median lethal concentration (LC50 - 96 h) to each formulation was determined, as well as the adverse effects of sublethal concentrations (½ LC50) on physiological and oxidative stress biomarkers after 96hs of exposure. The LC50 (96 h) values for EC and ME were 10 and 16.6 µg/L, respectively. Furthermore, in both EC and ME, the findings of physiological and oxidative stress aspects revealed significant markedly increases in serum total protein, albumin, globulin, and urea, as well as a significant decline in aminotransferases activity (ALT and AST), and creatinine levels (Cre). Moreover, superoxide dismutase (SOD), malondialdehyde (MDA), catalase (CAT), and glutathione peroxidase (GPx) were greatly increased, whereas glutathione-S-transferase (GST) and glutathione (GSH) were significantly reduced in the liver and brain. | ||
| Keywords | ||
| Abamectin; Formulations; Nile tilapia (Oreochromis niloticus); LC50; liver and kidney function; oxidative stress | ||
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