RETROSPECTIVE STUDY OF MANAGEMENT OF COW MILK PROTEIN ALLERGY IN INFANTS AND CHILDREN | ||
| Al-Azhar Journal of Pediatrics | ||
| Article 4, Volume 25, Issue 3, July 2022, Pages 2851-2859 PDF (205.34 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/azjp.2022.268935 | ||
| Abstract | ||
| Background: Cow's milk protein allergy (CMPA) represents one of the leading causes of food allergy in infants and young children. The immune reaction mainly due to casein and β-lactoglobulin protein. Many systems are affected specially GIT,respiratory system and skin. Aim of the work: To evaluate management of cow milk protein allergy in infant and children retrospectively. Patient and methods: This was Retrospective study that carried out on children who admitted in Al-Azhar Assiut University Hospital and Assiut Genetic Counseling Centre. During a period between 1st January 2019 and 28th February 2021. Result: Among the studied 150 case there were 119 (79.3%) with diarrhea, 54 (36%) with vomiting, 18 (12%) with constipation, 46 (30.7%) with abdominal distension, 53 (36%) with abdominal colic, 32 (21.3%) with eczema and 13 (8.7%) with respiratory distress, 60(40%) with occult blood in the stool,100(66.6) with +ve prickle test, the mean cow milk related symptoms scor (Co Miss score) of the studied cases was 18.95 (±4.72 SD) with range (12-32), number of children who used amino acids based formula has affordable response130(97%) and the number of children who used extensively hydrolyzed formula has affordable response 18(90%). Conclusion: Treatment by formulas has significantly reduced the morbidity associated with CMPA. The long-term management of CMPA involves prevention of inadvertent allergen exposure, and implementation of precautions against anaphylaxis. Patients require at least annual reassessment for tolerance development, as well as monitoring of dietary intake and growth parameters. If appropriately managed, the prognosis of CMPA is excellent. | ||
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