Use of Hyperbaric Oxygen in The Management of Rhino-Orbital-Cerebral Mucormycosis (Comparative Study) | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 192, Volume 89, Issue 2, October 2022, Pages 7395-7399 PDF (432.04 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2022.274806 | ||
| Authors | ||
| Mina Fayez Saleeb* ; Samia Ahmed Fawaz; Michael Rezk | ||
| Ain Shams university | ||
| Abstract | ||
| Introduction: Rhino-orbital-cerebral mucormycosis (ROCM) is considered a mortal disease induced by fungi. Mucormycosis is mostly found in patients suffering from diabetes mellitus, who performed organ transplantation, or in malignancy due to the immunocompromised state of these patients.Surgical intervention must be done, and better to do aggressive debridement for all involved tissues to attack the fungal load. Adjuvant therapies can be used, and among which is hyperbaric oxygen treatment (HBOT). Aim: This study aims to prove the effectiveness of HBOT in cases of Rhino-orbital-cerebral mucormycosis (ROCM) and whether it affects the outcome. Patients and Methods: The present study involved twelve patients presented by ROCM in the ENT Department, at Ain Shams University Hospital. Half of them received HBO in the hyperbaric chamber, while the other half were not treated with HBO. Results: Our results revealed the effectiveness of HBO as an adjunct therapy improving the outcome when it was added to both surgical debridement and antifungal therapy. Conclusion: HBOT can act as an adjunct therapy together with antifungal treatment and surgical debridement to improve the outcome in the treatment of ROCM. | ||
| Keywords | ||
| Hyperbaric oxygen; Rhino-orbital-cerebral mucormycosis (ROCM); Invasive fungal sinusitis | ||
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