Elsayed, M., Ahmed, A., Ahmed, E., Hassan, D., Sliem, M., Zewail, D., Sameh, S., Ibrahim, Y., Ibrahim, A., Ahmed, Y., Elsayed, N., Yasser, M., Deghedy, M., Abdellatief, M., Tarek, H., Awad, A., Mohamed, T., Mekky, R., Elgindi, O. (2023). A review on bioactive metabolites and great biological effects of Cranberry. test, 2(1), 177-209. doi: 10.21608/erurj.2023.190174.1009
Mahmoud Elsayed; Amal Ahmed; Esraa Ahmed; Donia Hassan; Mariem Sliem; Dalia Zewail; Shrouk Sameh; Yasmin Ibrahim; Abdelhady Ibrahim; Yara Ahmed; Nadia Elsayed; Mona Yasser; Maryam Deghedy; Mohamed Abdellatief; Heba Tarek; Amira Ibrahim Awad; Tasneem Mohamed; Reham Hassan Mekky; Omayma Elgindi. "A review on bioactive metabolites and great biological effects of Cranberry". test, 2, 1, 2023, 177-209. doi: 10.21608/erurj.2023.190174.1009
Elsayed, M., Ahmed, A., Ahmed, E., Hassan, D., Sliem, M., Zewail, D., Sameh, S., Ibrahim, Y., Ibrahim, A., Ahmed, Y., Elsayed, N., Yasser, M., Deghedy, M., Abdellatief, M., Tarek, H., Awad, A., Mohamed, T., Mekky, R., Elgindi, O. (2023). 'A review on bioactive metabolites and great biological effects of Cranberry', test, 2(1), pp. 177-209. doi: 10.21608/erurj.2023.190174.1009
Elsayed, M., Ahmed, A., Ahmed, E., Hassan, D., Sliem, M., Zewail, D., Sameh, S., Ibrahim, Y., Ibrahim, A., Ahmed, Y., Elsayed, N., Yasser, M., Deghedy, M., Abdellatief, M., Tarek, H., Awad, A., Mohamed, T., Mekky, R., Elgindi, O. A review on bioactive metabolites and great biological effects of Cranberry. test, 2023; 2(1): 177-209. doi: 10.21608/erurj.2023.190174.1009

A review on bioactive metabolites and great biological effects of Cranberry

ERU Research Journal
Article 6, Volume 2, Issue 1, January 2023, Pages 177-209    PDF (652.04 K)
Document Type: Review article
DOI: 10.21608/erurj.2023.190174.1009
Authors
Mahmoud Elsayed1; Amal Ahmed1; Esraa Ahmed1; Donia Hassan1; Mariem Sliem1; Dalia Zewail1; Shrouk Sameh1; Yasmin Ibrahim1; Abdelhady Ibrahim1; Yara Ahmed1; Nadia Elsayed1; Mona Yasser1; Maryam Deghedy1; Mohamed Abdellatief1; Heba Tarek1; Amira Ibrahim Awad1; Tasneem Mohamed1; Reham Hassan Mekky* 2; Omayma Elgindi2
1Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez road, 11829, Cairo, Egypt.
2Pharmacognosy Department, Faculty of Pharmacy, Egyptian Russian University, Badr CIty, Cairo-Suez Road, 11829, Cairo, Egypt
Abstract
The Cranberry (Genus Vaccinium) is characterized by its high content of acids, sugars and antioxidants. Some of the latter have been studied for their potential action against the adhesion of bacteria and a number of micro-organisms to the mucous membranes of the body. The effect observed is "mechanical" and not "bactericidal", so there is no risk of developing resistance phenomena. Cranberry and its juice were thus the first plant extracts in the world used to prevent the adhesion of Escherichia coli bacteria on the uro-epithelial cells lining the genitourinary tract and treat recurrent cystitis. It prevents stomach ulcers through prevention the attachment of Helicobacter Pylori bacteria to the stomach wall. Cranberry is used against dental plaque due to the anti-adhesion effect has positive repercussions on the formation of dental plaque and gum inflammation. Cranberry products, made from the North American cranberry, have long been thought to be effective in helping prevent urinary tract infections (is one of the most common infections in women, requiring antibiotic treatment.). The American cranberry, which is mainly consumed in the form of cranberry juice (CJ), is regarded as a promising functional food for the prevention of chronic diseases such as cancer, heart diseases, type 2 diabetes, and oral diseases. The phenolic compounds found in cranberry, like catechin and epicatechins, Flavonoids, Anthocyanins, phenolic acid, flavan-3-ol, flavonol glycoside, polyphenols, proanthocyanidins B-type, and other phenolic compounds are contributed to the reduction of oxidative stress.
Keywords
Cranberry; Urinary Tract Infections; anthocyanidins
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