fathy, A., zohairy, E., El Kady, N., Abdelrasheed, I., Abdel Fattah, A. (2023). COMPARISON BETWEEN THE MANAGEMENT AND OUTCOME OF TYPICAL AND ATYPICAL ANTIPSYCHOTIC DRUGS OVERDOSE: A STUDY FROM THE NATIONAL ENVIRONMENTAL AND CLINICAL TOXICOLOGY RESEARCH CENTRE, CAIRO UNIVERSITY HOSPITALS. test, 23(1), 111-119. doi: 10.21608/ejfsat.2023.177423.1282
ahmed ahmed fathy; eman zohairy; Nevine khairy El Kady; Iman Abdolmoneim Abdelrasheed; Amani Abdel Fattah. "COMPARISON BETWEEN THE MANAGEMENT AND OUTCOME OF TYPICAL AND ATYPICAL ANTIPSYCHOTIC DRUGS OVERDOSE: A STUDY FROM THE NATIONAL ENVIRONMENTAL AND CLINICAL TOXICOLOGY RESEARCH CENTRE, CAIRO UNIVERSITY HOSPITALS". test, 23, 1, 2023, 111-119. doi: 10.21608/ejfsat.2023.177423.1282
fathy, A., zohairy, E., El Kady, N., Abdelrasheed, I., Abdel Fattah, A. (2023). 'COMPARISON BETWEEN THE MANAGEMENT AND OUTCOME OF TYPICAL AND ATYPICAL ANTIPSYCHOTIC DRUGS OVERDOSE: A STUDY FROM THE NATIONAL ENVIRONMENTAL AND CLINICAL TOXICOLOGY RESEARCH CENTRE, CAIRO UNIVERSITY HOSPITALS', test, 23(1), pp. 111-119. doi: 10.21608/ejfsat.2023.177423.1282
fathy, A., zohairy, E., El Kady, N., Abdelrasheed, I., Abdel Fattah, A. COMPARISON BETWEEN THE MANAGEMENT AND OUTCOME OF TYPICAL AND ATYPICAL ANTIPSYCHOTIC DRUGS OVERDOSE: A STUDY FROM THE NATIONAL ENVIRONMENTAL AND CLINICAL TOXICOLOGY RESEARCH CENTRE, CAIRO UNIVERSITY HOSPITALS. test, 2023; 23(1): 111-119. doi: 10.21608/ejfsat.2023.177423.1282

COMPARISON BETWEEN THE MANAGEMENT AND OUTCOME OF TYPICAL AND ATYPICAL ANTIPSYCHOTIC DRUGS OVERDOSE: A STUDY FROM THE NATIONAL ENVIRONMENTAL AND CLINICAL TOXICOLOGY RESEARCH CENTRE, CAIRO UNIVERSITY HOSPITALS

The Egyptian Journal of Forensic Sciences and Applied Toxicology
Volume 23, Issue 1, March 2023, Pages 111-119    PDF (397.38 K)
Document Type: Original Article
DOI: 10.21608/ejfsat.2023.177423.1282
Authors
ahmed ahmed fathy1; eman zohairy1; Nevine khairy El Kady* 2; Iman Abdolmoneim Abdelrasheed3; Amani Abdel Fattah4
1Forensic and clinical toxicology department, Faculty of medicine, Cairo University
2forensic and clinical toxicology department, faculty of medicine, Cairo University, Cairo, Egypt.
3pharmacology department kasr alainy cairo University
4Forensic and Clinical Toxicology department, Faculty of Medicine, Cairo University
Abstract
Objectives: The purpose of this study was to assess the effect of management on the outcome of antipsychotic drugs overdose in Egypt.
Methodology: This study was conducted on 75 cases presented to National Environmental and Clinical Toxicology research Centre, Cairo university hospitals with antipsychotic medications toxicity, from April 2018 to September 2018.
Results: The most common presenting age group was age group B; from 18-40 years (45.3%), females (68%), belonging to urban population (82.7%), educated (96.2%) and not working (89.3%). The majority of cases presented with abnormal CNS manifestation; altered conscious level (97.3%), abnormal pulse; tachycardia (98.7%) and abnormal pupil size; mydriasis or miosis (52%). Most of the cases did not do drug screening (98.7%), neither did decontamination (66.7%) nor receive antidote (100%), but most of them received supportive measures. Most of the cases were admitted (90.7%) and stayed in hospital more than 24 hours and less than one week. Regarding the outcome, most of the cases were cured (92.6%).
Keywords
Antipsychotic Medications; Toxicity; management; Outcome
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