Saad, M., Abba, A., Musa, B., Ahmad, A., Muhammad, M. (2024). Neutrophils as a cellular marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria. test, 2(1), 12-18. doi: 10.21608/ijhegy.2023.247679.1039
Mairiga Saad; Abdallahi Abba; Bolanle Olufunke Priscilla Musa; Abdurrahman El-fulaty Ahmad; Musa Muhammad. "Neutrophils as a cellular marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria". test, 2, 1, 2024, 12-18. doi: 10.21608/ijhegy.2023.247679.1039
Saad, M., Abba, A., Musa, B., Ahmad, A., Muhammad, M. (2024). 'Neutrophils as a cellular marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria', test, 2(1), pp. 12-18. doi: 10.21608/ijhegy.2023.247679.1039
Saad, M., Abba, A., Musa, B., Ahmad, A., Muhammad, M. Neutrophils as a cellular marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria. test, 2024; 2(1): 12-18. doi: 10.21608/ijhegy.2023.247679.1039

Neutrophils as a cellular marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria

International Journal of Health Sciences (Egypt)
Article 2, Volume 2, Issue 1, January 2024, Pages 12-18    PDF (790.66 K)
Document Type: Original Article
DOI: 10.21608/ijhegy.2023.247679.1039
Authors
Mairiga Saad* 1; Abdallahi Abba2; Bolanle Olufunke Priscilla Musa3; Abdurrahman El-fulaty Ahmad4; Musa Muhammad5
1Ahmadu Bello University Zaria
2Pulmunonology Unit, Department of Medicine, Ahmadu Bello University, Zaria – Nigeria
3Immunology Unit, Department of Medicine, Ahmadu Bello University, Zaria – Nigeria
4Department of Medical Laboratory Science, Ahmadu Bello University, Zaria - Nigeria
5Ahmad1,3, Musa Mohammed1 Immunology Unit, Department of Medicine, Ahmadu Bello University, Zaria – Nigeria
Abstract
Background:  Tuberculosis (TB) remains a significant cause of morbidity and mortality worldwide. Complications of the disease is associated with the host’s inflammatory response. The study aimed to determine percentage neutrophil as a cellular biomarker of inflammation among adult patients with pulmonary tuberculosis in Zaria. Methods: This was a cross sectional study. Blood samples were taken from 30 treatment-naïve (TN), 30 treatment-experienced (TE) and 30 healthy controls (HC) for percentage neutrophils count. Results: The mean values of   percentage   neutrophils count for TN, TE and HC were 65.8 ± 7.3, 46.0 ± 11.8 and 55.8 ± 8.3, respectively. There was a decrease in neutrophils counts of TE patients compared with HC, an increased in neutrophils counts of TN compared with HC and a significant difference between TE and TN (P<0.0001).Conclusion Percentage Neutrophils should be use as a cellular biomarker for the monitoring of treatment response among adult patients with pulmonary Tuberculosis.
Keywords
Neutrophil; Tuberculosis; Biomarker; Inflammation
Statistics
Article View: 139
PDF Download: 123