H., H., M., A., Y., S., D., T. (2023). USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO CORRELATE PERIPAPILLARY CAPILLARY DENSITY TO PAPILLEDEMA GRADE IN IDIOPATHIC INTRACRANIAL HYPERTENSION. test, 6(2), 117-123. doi: 10.21608/ejco.2024.334198
Hamdy, H.; Amr, M.; Soliman, Y.; Tolba, D.. "USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO CORRELATE PERIPAPILLARY CAPILLARY DENSITY TO PAPILLEDEMA GRADE IN IDIOPATHIC INTRACRANIAL HYPERTENSION". test, 6, 2, 2023, 117-123. doi: 10.21608/ejco.2024.334198
H., H., M., A., Y., S., D., T. (2023). 'USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO CORRELATE PERIPAPILLARY CAPILLARY DENSITY TO PAPILLEDEMA GRADE IN IDIOPATHIC INTRACRANIAL HYPERTENSION', test, 6(2), pp. 117-123. doi: 10.21608/ejco.2024.334198
H., H., M., A., Y., S., D., T. USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO CORRELATE PERIPAPILLARY CAPILLARY DENSITY TO PAPILLEDEMA GRADE IN IDIOPATHIC INTRACRANIAL HYPERTENSION. test, 2023; 6(2): 117-123. doi: 10.21608/ejco.2024.334198

USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY TO CORRELATE PERIPAPILLARY CAPILLARY DENSITY TO PAPILLEDEMA GRADE IN IDIOPATHIC INTRACRANIAL HYPERTENSION

Egyptian Journal of Clinical Ophthalmology
Article 4, Volume 6, Issue 2, December 2023, Pages 117-123    PDF (549.57 K)
Document Type: Original articles: include clinical trials, interventional research, Basic researches and clinically relevant laboratory investigations
DOI: 10.21608/ejco.2024.334198
Authors
Hamdy, H.; Amr, M.; Soliman, Y.; Tolba, D.
Ophthalmology dept., Kasr Alainy, Faculty of Medicine, Cairo, Univ., Egypt.
Abstract
Purpose: Evaluation of the peripapillary microvascular density and neuronal changes in patients with idiopathic intracranial hypertension (IIH) in correlation with the degree of papilledema clinically at time of presentation. Methods: This case-control study included 112 eyes of 84 individuals. They were divided into IIH with papilledema group; 56 eyes of 28 patients and control group; 56 eyes of 56 healthy age and sex matched participants. Optical coherence tomography angiography (OCTA) to evaluate the Retinal nerve fiber layer (RNFL) and peripapillary capillary vessel density (CVD) was done with colored fundus photography for documentation of papilledema. Results: The difference in CVD and RNFL were statistically significant between both groups with lower vessel density and thicker RNFL in the IIH group. The thickness of the RNFL was correlated with the degree of papilledema unlike CVD. Conclusion: OCT-A revealed a reduction in the CVD, which could be caused by the thickening the RNFL due to swelling of the axons in the per-ipapillary area caused by papilledema. Overall, OCT-A has the ability to quantify CVD, identify areas of hypoperfusion, and spot early ischemic abnormalities in IIH patients before they develop optic nerve atrophy.
Keywords
IIH; peripapillary capillary vessel density; OCTA; Nerve fiber layer thickness
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