Elhadad, A., NIAZI, G., Elnaggar, H. (2024). The value of PET/CT combined with complementary MRI in the follow-up of hepatocellular carcinoma after transarterial chemoembolization.. test, 75(1), 141-150. doi: 10.21608/asmj.2023.244158.1179
Ahmed Fathy Abdou Elhadad; GAMAL ELDIN MOHAMED NIAZI; Heba Elnaggar. "The value of PET/CT combined with complementary MRI in the follow-up of hepatocellular carcinoma after transarterial chemoembolization.". test, 75, 1, 2024, 141-150. doi: 10.21608/asmj.2023.244158.1179
Elhadad, A., NIAZI, G., Elnaggar, H. (2024). 'The value of PET/CT combined with complementary MRI in the follow-up of hepatocellular carcinoma after transarterial chemoembolization.', test, 75(1), pp. 141-150. doi: 10.21608/asmj.2023.244158.1179
Elhadad, A., NIAZI, G., Elnaggar, H. The value of PET/CT combined with complementary MRI in the follow-up of hepatocellular carcinoma after transarterial chemoembolization.. test, 2024; 75(1): 141-150. doi: 10.21608/asmj.2023.244158.1179

The value of PET/CT combined with complementary MRI in the follow-up of hepatocellular carcinoma after transarterial chemoembolization.

Ain Shams Medical Journal
Volume 75, Issue 1, March 2024, Pages 141-150    PDF (741.01 K)
Document Type: Original Article
DOI: 10.21608/asmj.2023.244158.1179
Authors
Ahmed Fathy Abdou Elhadad* 1; GAMAL ELDIN MOHAMED NIAZI2; Heba Elnaggar3
1Ismailia general Hospital - Ismailia -Ministry of health, Egypt.
2Radiology department, Faculty of Medicine, Ain shams University, Cairo, Egypt.
3Department of Radiodiagnosis, Faculty of Medicine - Ain Shams University, Egypt.
Abstract
Background: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and the third leading cause of cancer-related death worldwide. Aim of the work: To assess the potential value of combining PET/CT and complementary MRI in the follow-up of HCC treated by trans-arterial chemo-embolization (TACE). Patients and Methods: This prospective study was done including forty patients having HCC treated by TACE. These patients were examined by 18F-FDG PET/CT combined with complementary MRI. PET/CT and MRI findings were analyzed. As a result, the included patients were divided into four groups; true positive, true negative, false negative and false positive. Serial alpha-fetoprotein levels were also reviewed. Results: By combining PET/CT and MRI findings, results were true positive in 14 patients, true negative in 14 patients, false negative in 9 patients and false positive in 3 patients. Consequently, true results represented 70%; whereas, false results represented 30%. Conclusion: The combination of PET/CT and complementary MRI did not have any added value in the follow-up of HCC after TACE.
Keywords
18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT); Magnetic resonance imaging (MRI); Hepatocellular carcinoma (HCC); trans-arterial chemo-embolization (TACE); Alpha-fetoprotein (AFP)
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