Effectiveness of Laser Acupoint Therapy and Exercise Program on Oxidative Stress and Antioxidant Response in Mild Essential Hypertensive Patients | ||
| Bulletin of Egyptian Society for Physiological Sciences | ||
| Article 14, Volume 30, Issue 2, June 2010, Pages 229-244 PDF (254.75 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/besps.2010.36310 | ||
| Authors | ||
| Hala Hamed* ; Mohamed Al Maghraby | ||
| Physical Therapy Department, College of Applied Medical Sciences, University of Dammam, Saudi Arabia | ||
| Abstract | ||
| Background and Purpose; Hypertension is associated with enhanced oxidative stress. Low-level laser therapy (LLLT) has been employed as a treatment for a variety of clinical conditions. Regular physical activity lowers blood pressure and enhances endothelial vasodilator function in hypertensive patients. The main purpose of the study was to measure the levels of serum Malondialdehyde (MDA) and Glutathione peroxidase (GPX) in relation to practicing laser acupuncture therapy and exercise program in mild essential hypertensive patients. Study Type and Design; Interventional, Randomized Control Trial. Subjects and Methods; 45-male patients (40-60 years) with mild essential hypertension were participated in the study. Following baseline measurements, patients were categorized randomly into three homogenous groups; laser therapy, exercise and control. Patients of laser therapy group subjected to a program of laser acupoint therapy to Chinese points for treating hypertension for 4 weeks. Patients of exercise group performed a supervised treadmill exercise program 3 times per week for 4 weeks. Data of pre- and post-intervention measures were collected and statistically analyzed. Results; Comparing postintervention results of laser therapy and control groups, and between exercise and control groups, showed a high statistically significant difference of mean values of MDA, systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse rate (PR), while serum GPX, showed nonsignificant (P>0.05) difference. Conclusions; Short-term (4-week) laser therapy and supervised treadmill exercise programs significantly improved MDA level. There was also a significant reduction in SBP and DBP, exhibiting a considerable hypotensive effect. It was found also that laser therapy is more efficient in improving the studied parameters than such improvements documented in exercise program. | ||
| Keywords | ||
| Essential hypertension; Oxidative Stress; Malondialdehyde; glutathione peroxidase; Laser Acupoint; Exercise Program | ||
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