Immune System Response to Aerobic Exercise Training in Obese Females | ||
| Bulletin of Egyptian Society for Physiological Sciences | ||
| Article 13, Volume 28, Issue 1, June 2008, Pages 171-182 PDF (173.45 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/besps.2008.36847 | ||
| Authors | ||
| Azza Ismail* 1; Shehab Kader1; Soheir Abo EL Fadl2; Nashwa El Tablawy3 | ||
| 1Department of Physical Therapy for Cardiopulmonary Disorders and Geriatrics, Faculty of Physical Therapy, Cairo University | ||
| 2Internal Medicine Department, Faculty of Medicine, Cairo University | ||
| 3Physiology Department, Faculty of Medicine, Cairo University | ||
| Abstract | ||
| Background: Obesity has a bad impact on immune system; on the other hand moderate exercise increases the resistance to infection. The aim of this study was to determine the response of complement system to aerobic exercise training in obese females. Subjects and methods:Thirty obese females participated in this study and they were divided randomly into two equal groups; the exercise group (group-1) which received aerobic exercise training for 4 months and the non-exercised group (group-2) which maintained their ordinary life style. Thirty age-matched non-obese females were the control group. Measurements of serum complement proteins (C3 and C4) were done at the start and at the end of the study, also the body mass index (BMI) was calculated at the start and at the end of the study. Results:at the start of the study; there was a significantly high levels of C3 & C4 in obese compared to the control (non-obese) females (P=0.000). At the end of the study; there was a significant decrease in BMI, C3 & C4 in the exercise group compared to the non-exercised group, also there was a significant differences between the measures at the start and at the end of the study in the exercise group as regards BMI, C3 & C4. Conclusion: obesity causes changes in the immune system as documented by increase in C3 & C4 levels. Moderate aerobic exercise produced weight reduction and decreased the abnormally elevated complement components (C3 & C4) in obese females; so improving the immune system. | ||
| Keywords | ||
| complement system; Aerobic exercise; immunity and obesity | ||
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