The Role of Diffusion Weighted Magnetic Resonance Imaging in Assessment of Axillary Lymph Node Metastasis in Patients with Breast Cancer Using Two Cut off Values | ||
| SECI Oncology Journal | ||
| Volume 12, Issue 3, July 2024, Pages 308-316 | ||
| Abstract | ||
| Background: Axillary lymph nodes (ALNs) metastasis is very important for the prognosis of breast cancer cases, affecting their survival rate but until now, tissue biopsy is the only golden standard for definite diagnosis. The current work evaluates the feasibility of Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) in prediction of ALN metastasis in breast cancer. Methods: A total of 300 ALNs were surgically excised from 30 women with confirmed as breast cancer. MRI with diffusion examination was performed and comparison between MRI findings with postoperative histopathology was done in lymph Nodes (LNs) with short axis diameter > 5 mm. Results: By imaging It was found that MRI with diffusion had comparable accuracies with LNs > 5 mm in size (accuracy in both conditions was 59%). Also, accuracy of adherent diffusion coefficient is better when its cutoff point for malignant LNs ≤ 0.90 than ≤ 0.80 (65.3% vs.61.7%; respectively). Conclusion: MRI is considering essential maneuver in preoperative LN evaluation of BC, MRI with diffusion and ADC values are showing accepted specificity and accuracy in LN assessment. | ||
| Keywords | ||
| Breast cancer; Axillary lymph nodes; Diffusion weighted magnetic resonance imaging; Adherent diffusion coefficient | ||
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