“The influence of female body mass index, menstrual cycle phase and age on propofol injection pain” | ||
| Egyptian Journal of Anaesthesia | ||
| Volume 37, Issue 1, January 2021, Pages 273-280 PDF (376.92 K) | ||
| DOI: TEJA-2021-0053 | ||
| Authors | ||
| Raham Hasan Mostafa; Mohamed Mohamed Kamal; Marwa Mamdouh Mohamed; Mohamed Abdulmohsen Ismaiel | ||
| Abstract | ||
| : Eliminating propofol injection pain (PIP) should be multimodal, including pharmacological and non-pharmacological interventions. Understanding risk factors – body mass index, menstrual cycle phase and age for example – leading to increased pain sensitivity will identify patients at most risk for PIP, permitting effective treatment strategies to be initiated at an early stage. : Our goal is to determine occurrence and severity of propofol injection pain among female patients, whether they are obese or non-obese, during different menstrual cycle phases. : A prospective observational study. : Single university teaching hospital’s operating rooms. : 84 female undergoing surgeries under general anesthesia, classified as American Society of Anesthesiologists (ASA) physical status I–II, between 18 and 65 years of age were enrolled. : We evaluated propofol injection pain using visual analogue scale (VAS) during induction of general anesthesia. : The relation between propofol induced peripheral venous pain and female body mass index, menstrual cycle phase and age. : 71.4% of patients experienced PIP. Of those patients who experienced PIP; 40.5% (34/84 patients) had moderate to severe pain. Age <35 years was the only independent predictor of moderate/severe PIP (sensitivity 62%, specificity 78%). After adjustment for age category, there was no statistically significant association between occurrence of moderate/severe PIP and obesity or menstruation. : Propofol injection pain prophylactic measures should be considered in young females <35 years as they may be more prone to moderate/severe PIP. : NCT04078087 | ||
| Keywords | ||
| Body Mass Index; Menopause; menstrual cycle; obese; Propofol Injection Pain; visual analogue scale | ||
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