Special maternal care bundle to attenuate post-spinal hypotension in cesarean section: A randomized controlled clinical trial | ||
| Egyptian Journal of Anaesthesia | ||
| Volume 39, Issue 1, December 2023, Pages 296-303 PDF (555.18 K) | ||
| DOI: TEJA-2022-0255 | ||
| Authors | ||
| Abdelrhman Alshawadfy; Shaimaa A. Dahshan; Ahmed A. Ellilly; Ahmed M. Elewa | ||
| Abstract | ||
| Background This study aimed to assess the safety and efficacy of a special maternal care bundle as an alternative technique for the attenuation of hypotension following spinal anesthesia in parturients scheduled for CS. Methods This double-blinded, parallel-group, randomized trial enrolled 138 adult parturients who were scheduled for CS under spinal anesthesia. The patients were randomly allocated to two groups. In the care bundle group, 68 participants received a co-load of lactated Ringer’s solution and ondansetron infusion during administration of spinal anesthesia with a slow rate intrathecal bupivacaine injection and a V-shaped supine position. While in the best practice group, 70 participants received a co-loaded lactated Ringer’s solution during spinal anesthesia with early use of vasopressors and a left uterine tilting position. The primary outcome was the total ephedrine consumption. Secondary outcomes included the mean arterial blood pressure, heart rate, atropine usage, complications such as dizziness, nausea, and vomiting, as well as the baby’s Apgar score. Results Special maternal care bundle significantly reduced the need and the total dose of ephedrine ( = 0.042). The mean arterial blood pressure was significantly less affected by maternal bundle care, but the reduction in heart rate, the need for atropine, the incidence of dizziness, nausea, vomiting, and the Apgar score were comparable in both groups. Conclusion The special maternal care bundle including co-load of lactated ringer, ondansetron 4 mg IV infusion, slow intrathecal injection and v-shaped positions can reduce the incidence of hypotension resulting from spinal anesthesia and ephedrine usage during CS. | ||
| Keywords | ||
| Care Bundle; Ephedrine; hypotension; Multimodal; Spinal anesthesia | ||
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