Hasanein, R., El-Sayed, W. (2014). The effect of ondansetron in preventing the hypotensive bradycardic events during shoulder arthroscopy done under interscalene block in the sitting position. test, 30(3), 305-310. doi: 10.1016/j.egja.2014.02.002
Riham Hasanein; Wael El-Sayed. "The effect of ondansetron in preventing the hypotensive bradycardic events during shoulder arthroscopy done under interscalene block in the sitting position". test, 30, 3, 2014, 305-310. doi: 10.1016/j.egja.2014.02.002
Hasanein, R., El-Sayed, W. (2014). 'The effect of ondansetron in preventing the hypotensive bradycardic events during shoulder arthroscopy done under interscalene block in the sitting position', test, 30(3), pp. 305-310. doi: 10.1016/j.egja.2014.02.002
Hasanein, R., El-Sayed, W. The effect of ondansetron in preventing the hypotensive bradycardic events during shoulder arthroscopy done under interscalene block in the sitting position. test, 2014; 30(3): 305-310. doi: 10.1016/j.egja.2014.02.002

The effect of ondansetron in preventing the hypotensive bradycardic events during shoulder arthroscopy done under interscalene block in the sitting position

Egyptian Journal of Anaesthesia
Volume 30, Issue 3, July 2014, Pages 305-310    PDF (482.28 K)
DOI: 10.1016/j.egja.2014.02.002
Authors
Riham Hasanein; Wael El-Sayed
Abstract
Purpose
This study was conducted to test whether blocking the serotonin receptors by intravenous [IV] ondansetron; can help in reducing the hypotensive bradycardic events [HB events] associated with shoulder arthroscopy done in the sitting position under interscalene plexus block [ISB].
Methods
One hundred and fifty patients, scheduled for shoulder arthroscopy in the sitting position under ISB, were randomly assigned to one of three groups receiving either: 4 mg ondansetron, or 8 mg ondansetron or saline.
Results
IV injection of ondansetron 4 mg or 8 mg significantly reduced the incidence of HB events from 20.4% in the saline group to 6.1% after injection of 4 mg ondansetron and 6% after injection of 8 mg ondansetron; value [0.030].
Conclusion
IV ondansetron either 4 mg or 8 mg reduces the HB events during shoulder arthroscopy in the sitting position under ISB.
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