Helicobacter Pylori Screening in pregnant women with and without Hyperemesis Gravidarum | ||
| Sohag Medical Journal | ||
| Volume 29, Issue 1, 2025, Pages 146-153 PDF (663.14 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/smj.2025.357454.1531 | ||
| Authors | ||
| Hatem Aboelftooh Awaga* 1; Amr Ayman Hassan2; Mohey Eldin Hassan3; Sabri Mahmoud Muhammad4; Mamdouh Elsemary Ayed5 | ||
| 1Department of Obstetrics and Gynecology, Faculty of medicine, Sohag University, Egypt. | ||
| 2Obstetrics and Gynecology department, Sohag university, Sohag, Egypt | ||
| 3Analysis and Laboratories Department, Higher Technological Institute of Applied Health Sciences in Sohag, Ministry of Higher Education, Cairo, Egypt | ||
| 4Obstetrics and Gynecology department, Sohag University, Sohag, Egypt | ||
| 5Obstetrics and Gynecology department, Sohag University, Sohag, Egypt. | ||
| Abstract | ||
| Aim: To evaluate the prevalence of H. pylori infection among pregnant women with hyperemesis gravidarum (HG) in comparison to pregnant women without (HG). Methods: A cross-sectional trial was carried out on 113 pregnant women (<16 weeks) that were divided into a positive HG group (n=63) and a negative HG group (n=50). Fresh stool samples were in airtight containers until the stool antigen tests were done on all patients. Results: Age was significantly lower in the positive HG group than the negative HG group (P<0.005). Gestational age and crown-rump length were significantly lower in the positive HG group than the negative HG group (P<0.05). The number of vomits was significantly higher in the positive HG group than the negative HG group (P<0.00001). Complete blood count, direct bilirubin, indirect bilirubin, and total bilirubin were significantly higher in the positive HG group than in the negative HG group (P<0.001). Potassium (K⁺) and sodium (Na⁺) were significantly lower in the positive HG group than in the negative HG group (P<0.001). Ketonuria was significantly higher in the positive HG group than the negative HG group (P<0.001) and finally, H pylori testing was not significantly different in both studied groups (P=0.560). Conclusions: The present study demonstrated that the occurrence of H. pylori infection was comparable in pregnant women with and without hyperemesis gravidarum (HG). Trial registration: The study was registered prospectively on ClinicalTrials.gov with trial registration number (NCT05835076). | ||
| Keywords | ||
| Antigen Test; Early Pregnancy; Helicobacter Pylori; Hyperemesis Gravidarum; Stool Analysis | ||
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