M. Osman, R., Fayez, M., EL-Helw, H., EL-Meneisy, A. (2010). Recent formulation for polyvalent Clostridial vaccine. test, 20(1), 116-121. doi: 10.21608/jvmr.2020.77587
Roukaia M. Osman; M. M. Fayez; H. A. EL-Helw; A. EL-Meneisy. "Recent formulation for polyvalent Clostridial vaccine". test, 20, 1, 2010, 116-121. doi: 10.21608/jvmr.2020.77587
M. Osman, R., Fayez, M., EL-Helw, H., EL-Meneisy, A. (2010). 'Recent formulation for polyvalent Clostridial vaccine', test, 20(1), pp. 116-121. doi: 10.21608/jvmr.2020.77587
M. Osman, R., Fayez, M., EL-Helw, H., EL-Meneisy, A. Recent formulation for polyvalent Clostridial vaccine. test, 2010; 20(1): 116-121. doi: 10.21608/jvmr.2020.77587

Recent formulation for polyvalent Clostridial vaccine

Journal of Veterinary Medical Research
Article 15, Volume 20, Issue 1, March 2010, Pages 116-121    PDF (232.15 K)
DOI: 10.21608/jvmr.2020.77587
Authors
Roukaia M. Osman1; M. M. Fayez1; H. A. EL-Helw1; A. EL-Meneisy2
1Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt.
2eterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt.
Abstract
Polyvalent clostridial vaccine has been prepared according to L+ dose of C. perfringens type B and D, C. septicum, C. oedematiens, the optical density of C. chauvoei, and flocculation test of C. tetani. The vaccine has been evaluated in guinea pigs, rabbits and sheep. It gave high protective immunity in guinea pigs in challenge test (100% protection), the sera of vaccinated rabbits gave high titers more than the permissible limit. Sera of vaccinated sheep showed high antibody titer and good immune response which revealed that the vaccine able to protect sheep against clostridial diseases. The recent formulation of polyvalent clostridial vaccine is very useful tool for production of highly antigenic multicomponent clostridial vaccine used for control of different clostridial diseases.
Keywords
Recent; formulation; polyvalent; Clostridial; vaccine
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