Al-Meligi, N., Shaheen, M., Mahmoud, M., Al Husseiny, R. (2018). Evaluation of the clinical efficacy of Fractional CO2 laser combined with topical antifungal in the treatment of onychomycosis using SCIO (Score clinical index of onychomycosis). test, 72(4), 4313-4319. doi: 10.21608/ejhm.2018.9245
Norhan K.M. Ali Al-Meligi; Maha A. Shaheen; Mohammed T. Mahmoud; Rania M. Al Husseiny. "Evaluation of the clinical efficacy of Fractional CO2 laser combined with topical antifungal in the treatment of onychomycosis using SCIO (Score clinical index of onychomycosis)". test, 72, 4, 2018, 4313-4319. doi: 10.21608/ejhm.2018.9245
Al-Meligi, N., Shaheen, M., Mahmoud, M., Al Husseiny, R. (2018). 'Evaluation of the clinical efficacy of Fractional CO2 laser combined with topical antifungal in the treatment of onychomycosis using SCIO (Score clinical index of onychomycosis)', test, 72(4), pp. 4313-4319. doi: 10.21608/ejhm.2018.9245
Al-Meligi, N., Shaheen, M., Mahmoud, M., Al Husseiny, R. Evaluation of the clinical efficacy of Fractional CO2 laser combined with topical antifungal in the treatment of onychomycosis using SCIO (Score clinical index of onychomycosis). test, 2018; 72(4): 4313-4319. doi: 10.21608/ejhm.2018.9245

Evaluation of the clinical efficacy of Fractional CO2 laser combined with topical antifungal in the treatment of onychomycosis using SCIO (Score clinical index of onychomycosis)

The Egyptian Journal of Hospital Medicine
Article 14, Volume 72, Issue 4, July 2018, Pages 4313-4319    PDF (347.22 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2018.9245
Authors
Norhan K.M. Ali Al-Meligi* ; Maha A. Shaheen; Mohammed T. Mahmoud; Rania M. Al Husseiny
Dermatology, Venerology and Andrology Department, Faculty of Medicine - Ain Shams University
Abstract
Background: Onychomycosis, a fungal infection of the nail, is considered one of the most prevalent disorders of the nail. Score clinical index of onychomycosis (SCIO) enable comparison of the severity of onychomycosis between nails despite differences in the clinical presentation. Recently fractional CO2 laser and topical antifungal were found to be effective in treating onychomycosis.
Aim of the Work: To evaluate the clinical efficacy of fractional carbon dioxide laser combined with topical antifungal in treatment of onychomycosis.
Patients and Methods: The present study included 20 patients with toenail and fingernail onychomycosis of all age groups. The affected nails received 3 sessions of laser therapy (Fractional CO2 laser) at 4 weeks intervals and once daily application of topical antifungal (Oxiconazole) available at the market under the name tinox cream.
Conclusion: We concluded that fractional carbon-dioxide laser therapy, combined with a topical antifungal agent, is effective in the treatment of onychomycosis. It can treat different types of onychomycosis safely and effectively and is especially suitable for older patients with low immunity or liver and renal dysfunction who are not appropriate candidates for systemic antifungal agents. Thus, it could be considered as an alternative treatment modality.
Keywords
CO2: Carbon dioxide; DLSO: Distal-lateral subungual onychomycosis; SCIO: Score clinical index of onychomycosis
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